Foundayo (orforglipron)

The Wegovy pill has only recently been approved in the UK by the medicines regulator, the MHRA. It is expected to become available to order from Lotus Weight Loss Clinic at the start of July, subject to confirmed UK supply and pharmacy availability.

If you are interested in starting the Wegovy pill, switching from Wegovy or Mounjaro injections, or restarting treatment after a break, please join our priority update list. We’ll contact you as soon as we have confirmed launch details, pricing, and ordering information.

Join the Wegovy pill waitlist here: https://www.lotusweightloss.co.uk/pages/weight-loss-pill

The exact Wegovy pill price in the UK has not yet been confirmed. However, it is expected that Wegovy tablets will be priced similarly to Wegovy injections which start around £99 per month for the lowest dose, although this may vary depending on the dose, supplier pricing, pharmacy dispensing costs, and the level of clinical support included.

At Lotus Weight Loss Clinic, we will confirm the Wegovy pill cost as soon as UK pricing and availability are finalised. If you are interested in starting oral Wegovy, you can join our waitlist and we will update you when the Wegovy pill becomes available.

The Wegovy pill will be a prescription-only medicine, so the total cost may include an online consultation, prescriber review, ongoing monitoring, and medication supply.

Yes. If you are interested in starting Wegovy tablets, switching from injections, or restarting treatment after a break, you can join the Lotus Weight Loss Clinic Wegovy Pill waitlist.

Our clinical team will update you when the treatment becomes available (expected early July 2026) and help assess whether the Wegovy pill is suitable for your circumstances.

The Wegovy pill is an oral weight loss medication that contains semaglutide. Semaglutide is a GLP-1 receptor agonist, which means it mimics a natural appetite-regulating hormone in the body.

It helps with weight loss by reducing hunger, helping you feel fuller for longer, slowing stomach emptying, and supporting a lower calorie intake alongside lifestyle changes.

The Wegovy pill may appeal to three main groups of patients.

The Wegovy pill may be suitable for adults with:

Weight-related health conditions may include high blood pressure, high cholesterol, prediabetes, type 2 diabetes, sleep apnoea, or other obesity-related conditions.

A clinician will also check your medical history, current medication, previous GLP-1 use, side effects, pregnancy plans, and whether another treatment may be more suitable.

Take one Wegovy tablet once daily, preferably when you first wake up.

For best absorption:

Do not take it with tea, coffee, juice, fizzy drinks, or food. Taking it incorrectly can reduce how much semaglutide your body absorbs.

Some people notice reduced appetite, fewer cravings, or feeling fuller within the first few days or weeks.

Visible weight loss usually takes longer. The most noticeable results are often seen after dose escalation, particularly once patients reach the higher treatment doses.

In clinical studies, Wegovy 25mg tablets helped patients lose a significant amount of weight when used alongside diet and lifestyle changes.

Average results vary, but studies showed weight loss of around 14% to 17% over 64 weeks, depending on how results were measured. Some people lose more, and some lose less.

The best results are usually seen when treatment is combined with a reduced-calorie diet, higher protein intake, regular activity, and ongoing clinical support.

Not necessarily. The best option depends on your routine, treatment history, side effects, weight loss goals, and personal preference.

The Wegovy pill contains semaglutide, the same active ingredient as Wegovy injections, but it is taken as a daily tablet instead of a weekly injection. For some people, the convenience of a tablet may make treatment easier to start or easier to stick with.

In clinical trials, the Wegovy pill has shown strong weight loss results. In the OASIS 4 trial, people taking Wegovy 25mg tablets lost an average of 13.6% of their starting body weight after 64 weeks, compared with 2.2% with placebo. When looking at patients who stayed on treatment without additional weight loss therapies, average weight loss was estimated at 16.6%.

Wegovy injections have also shown strong results. In the STEP 1 trial, people taking Wegovy 2.4mg weekly injections lost an average of 14.9% of their starting body weight after 68 weeks, compared with 2.4% with placebo. In patients who stayed on treatment, average weight loss was estimated at 16.9%.

There is also now a newer higher-dose Wegovy 7.2mg weekly injection for suitable adults with obesity. In the STEP UP trial, Wegovy 7.2mg injection showed average weight loss of around 21% after 72 weeks. This may make the 7.2mg injection an option for some patients who need a higher maintenance dose, but it is not suitable for everyone and should only be used if prescribed.

This means the Wegovy pill may offer similar weight loss results to the standard Wegovy 2.4mg injection for some patients, while offering the benefit of being needle-free. The newer Wegovy 7.2mg injection may offer greater average weight loss for suitable patients, but it involves a higher injectable dose and may not be appropriate for everyone.

Results vary from person to person. Wegovy tablets must also be taken correctly every morning on an empty stomach to work properly.

You may prefer the Wegovy pill if you:

Yes, some patients can switch from Wegovy injections to Wegovy tablets, but this must be reviewed by a prescriber.

The official switching position is strongest for patients already stable on Wegovy 2.4mg weekly, who may be able to move to Wegovy 25mg tablets once daily one week after their last injection.

Wegovy injection to Wegovy pill switching guide

If you are already using Wegovy injections, you may be able to switch to the Wegovy pill. The table below shows the estimated Wegovy pill dose that may be recommended based on your current Wegovy injection dose.

This switching guide is extrapolated from the Wegovy pill Summary of Product Characteristics from the manufacturer, which is expected to be published on the MHRA products website within 7 days of approval: https://products.mhra.gov.uk/

This switching method is considered off-label, meaning it has not been formally evaluated in clinical trials. However, real-world data and clinical experience when switching between GLP-1 medicines suggest that many patients tolerate the transition well, with side effects generally limited to those commonly seen with GLP-1 treatments, such as nausea, constipation, diarrhoea, reflux, or reduced appetite.

Your Wegovy pill dose should always be confirmed by a prescriber after reviewing your current dose, side effects, medical history, and how long you have been using Wegovy injections. If you are a new customer then you can complete our online consultation form which will guide you through the switching process, and if you are an existing customer you can log in to your Lotus account and click 'Re-order' and then choose to change your medication.

Yes, patients may be able to switch from Mounjaro to the Wegovy pill, but this is not a direct like-for-like dose conversion.

Mounjaro contains tirzepatide, which works on both GIP and GLP-1 receptors. Wegovy contains semaglutide, which is a GLP-1 receptor agonist. Because they are different medicines, the doses cannot be matched exactly.

Mounjaro to Wegovy pill switching guide

If you are currently using Mounjaro, the table below shows the estimated Wegovy pill dose that may be recommended based on your current Mounjaro dose.

This switching guide is based on clinical judgement and extrapolated dose comparisons. Switching from Mounjaro to the Wegovy pill is considered off-label, meaning it has not been formally evaluated in clinical trials.

However, real-world data and clinical experience when switching between GLP-1 medicines suggest that many patients tolerate the transition well, with side effects generally limited to those commonly seen with GLP-1 treatments, such as nausea, constipation, diarrhoea, reflux, or reduced appetite.

You should not use Mounjaro and Wegovy together. Your prescriber will advise when to stop Mounjaro and when to start Wegovy tablets, based on your current dose, side effects, treatment history, and weight loss progress.

If you are a new customer then you can complete our online consultation form which will guide you through the switching process, and if you are an existing customer you can log in to your Lotus account and click 'Re-order' and then choose to change your medication.

Yes, the Wegovy pill can be used for weight maintenance as well as weight loss, if it remains clinically suitable for you.

Many people think of GLP-1 treatment as something used only to lose weight, but maintaining weight loss is often the harder part. After you reach your target weight, your prescriber may recommend continuing the Wegovy pill to help keep your appetite under control and reduce the risk of weight regain.

The usual maintenance dose of the Wegovy pill is 25mg once daily, although some patients may stay on a lower dose for longer if this is more suitable or better tolerated.

If you stop taking Wegovy, your appetite may gradually return, and some weight regain is possible, especially if lifestyle changes are difficult to maintain. This does not mean you are “dependent” on the medication, but it does reflect that obesity is a long-term condition for many people.

At Lotus Weight Loss Clinic, we support thousands of GLP-1 maintenance patients with long-term, structured help to maintain their results. Our maintenance programme is designed for people who want to keep the weight off, protect their progress, and build habits that last beyond the medication alone.

You can join Lotus for maintenance even if you currently get your medication from another supplier, as long as your BMI is 20 or above and you have used your GLP-1 medication within the last 6 months. You can also join Lotus and switch to the Wegovy pill at the same time, if it is suitable for you.

Switching is simple and can usually be completed in around 2 minutes using our online consultation form. A Lotus prescriber will review your current treatment, BMI, medical history, side effects, and goals before confirming whether Wegovy tablets are appropriate.

Lotus maintenance patients also get access to our structured 12-week maintenance education course in the app. This covers the key areas that help people maintain their results long term, including nutrition, movement, habit formation, appetite management, mindset, and relapse prevention.

You will also be able to join our thriving maintenance community, where patients can share progress, ask questions, and stay motivated with others who are working to maintain their weight loss.

The most common side effects are usually digestive and are more likely when starting treatment or increasing dose.

Common Wegovy pill side effects include:

• feeling sick
• vomiting
• diarrhoea
• constipation
• stomach pain
• indigestion or reflux
• bloating or wind
• headache
• tiredness
• dizziness
• taste changes

Most side effects are mild to moderate and improve as your body adjusts. Eating smaller meals, avoiding greasy foods, drinking enough fluids, and increasing doses gradually can help.

Because Wegovy tablets slow stomach emptying and have specific absorption requirements, your prescriber needs to know about all medicines you take.

This is especially important if you take:

• levothyroxine
• warfarin or similar blood-thinning medicines
• insulin
• sulfonylureas
• oral contraceptives
• medicines that must be taken first thing in the morning

You must wait at least 30 minutes after taking Wegovy before taking other oral medicines. Our online consultation will assess to see if you are eligible to use the Wegovy pill based on your current medications. 

No. Wegovy should not be used during pregnancy or breastfeeding.

If you are planning a pregnancy, you should stop semaglutide at least 2 months before trying to conceive. You should use effective contraception while taking Wegovy.

If you become pregnant while taking Wegovy, stop treatment and speak to a healthcare professional.

If you miss a dose, skip the missed tablet and take your next dose the following morning.

Do not take two tablets on the same day to make up for a missed dose. Missing doses regularly can reduce the effectiveness of treatment.

The Wegovy pill is not currently available on the NHS. NHS access will depend on NICE guidance, local availability, and eligibility criteria.

Private treatment may become available before NHS prescribing pathways are confirmed.